Position: Lecturer
School/Academic Group: School of Pharmaceutical Sciences

Email: yajie_wang@whu.edu.cn

Education:

2002/09 - 2006/06: Huazhong Agricultural University, Bachelor of Science

2006/09 - 2009/06: State Key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University, Master

2009/09 - 2013/01: Chinese Academy of Sciences, Ph.D.

Working Experience:

2013/01 - 2016/03: Wuhan University, School of Pharmaceutical Sciences, Postdoc

2016/03 - Present: Wuhan University, School of Pharmaceutical Sciences, Lecturer

Research Interests:

Function of Pathogenic Genes of Alzheimer's Disease, DNA Phosphorothioation Modification

Publications:

1.  Yajie Wang, Zhe Wang, Bharat H. Joshi, Raj K. Puri, Brian Stultz, Qing Yuan,Yujie Bai, Pingkun Zhou, Zengqiang Yuan, Deborah A. Hursh, Xiaolin Bi. The Tumor Suppressor Caliban Regulates DNA Damage Induced Apoptosis Through p53-Dependent and -Independent Activity. Oncogene 2013(32): 3857–3866.

2.  Yajie Wang, Fengyi Wu, Haining Pan, Wenzhong Zheng, Chi Feng, Yunfu Wang, Zixin Deng, Lianrong Wang, Jie Luo,Shi Chen. Lost region in amyloid precursor protein (APP) through TALEN mediated genome editing alters mitochondrial morphology. Scientific Reports 2016(6): 22244 DOI: 10.1038/srep22244.

3.  Li Yuanjiao, Liu Jingjing, Wang Yajie, Chan Ho-Wai, Wang Lianrong and Chan Wan. Mass spectrometric and spectrophotometric analyses reveal an alternative structure and a new formation mechanism for melanin. Analytical Chemistry 2015, 87(15)：7958-7963.

4.  Nian Wang, Yajie Wang, Fang Tian, Graham J. King, Chunyu Zhang , Yan Long , Lei Shi , Jinling Meng , A functional genomics resource for Brassica napus: development of an EMS mutagenized population and discovery of FAE1 point mutations by TILLING. New Phytologist 2008, 180(4): 751-765.

5.  Chengli Ding, Zhifei Wu, Lei Huang, Yajie Wang, Zixin Deng, Lianrong Wang, and Zhiyin Song and Shi Chen. Mitofilin and CHCHD6 physically interact with Sam50 to sustain cristae structure. Scientific Reports2015(5):16064 DOI: 10.1038/srep16064.

6.  Wei He, Teng Huang, You Tang, Yanhua Liu, Xiaolin Wu, Si Chen, Wan Chan, Yajie Wang, Xiaoyun Liu, Shi Chen and Lianrong Wang. Regulation of DNA phosphorothioate modification in Salmonella enterica by DndB. Scientific Reports 2015(5): 12368. DOI: 10.1038/srep12368.

7.  Nian Wang, Yue Xiang, Linchuan Fang, Yajie Wang, Haiping Xin, Shaohua Li, Patterns of Gene Duplication and Their Contribution to Expansion of Gene Families in Grapevine. Plant Mol Biol Rep 2013, 31(4):852-861.