Position: Associate Professor

School/Academic Group: School of Pharmaceutical Sciences

Email： tangj0205@whu.edu.cn

Education:

1987.09 - 1991.07  Jilin Agricultural University，Bachelor

1991.09 - 1994.07 Wuhan Botanical Garden, Chinese Academy of Sciences，Master

2000.09 - 2003.06 China Pharmaceutical University，Ph.D.

Working Experience:

2004.02-2007.01 The University of Hong Kong, Assistant Researcher

2007.02-now  Wuhan University, Associate Professor

Current Teaching Interests/Responsibilities:
Experiment of Pharmacognosy

Research Interests:

Biotransformation, chemical pharmacology and metabolomics of traditional Chinese medicine and its active ingredients; Pharmacognosy research and quality evaluation based on modern analytical technology; Research and development of natural active ingredient chemistry and botanical medicine.

Publications: (*: Corresponding author)

1. Chen, Xiang; Liu, Menghan; Tang, Jun*; Wang, Ning; Feng, Yibin*; Ma, Haotian. Research Progress on the Therapeutic Effect of Polysaccharides on Non-Alcoholic Fatty Liver Disease through the Regulation of the Gut-Liver Axis. International Journal of Molecular Sciences, 2022, 23(19), 11710. https://doi.org/10.3390/ijms231911710.

2. Liu, Wenju; Li, Xu; Zhou, Bo; Fang, Shoucai; Ho, Wenzhe; Chen, Hui; Liang, Hao; Ye, Li*; Tang, Jun*. Differential induction of apoptosis and autophagy by pyrrolizidine alkaloid clivorine in human hepatoma Huh-7.5 cells and its toxic implication. PLoS ONE 2017, 12(6): e0179379. https://doi.org/10.1371/journal.pone.0179379.

3. Song, Xueping; Tang, Jun*. Extraction optimization, preliminary characterization and bioactivities in vitro of Ligularia hodgsonii polysaccharides. International Journal of Molecular Sciences 2016, 17(5): 788; doi:10.3390/ijms17050788.

4. Zhou, Zihao; Tang, Jun*; Song, Xueping. Chemical Composition of the Essential Oil of Ligularia hodgsonii and Free Radical Scavenging Activity of the Oil and Crude Extracts. Natural Product Communications 2014, 9(10): 1511-1514.

5. Tang, Jun*; Cheng, Min; Hattori, Masao. Pyrrolizidine alkaloid profile in a traditional Chinese herbal medicine Chuan Zi Wan (Ligulariae Radix et Rhizoma) by liquid chromatography/electrospray ionization ion trap mass spectrometry. Analytical Methods 2012, 4: 2797-2808.

6. Tang, Jun; Feng, Yibin*; Tsao, Saiwah; Wang, Ning; Curtain, Robert; Wang, Youwei. Berberine and Coptidis Rhizoma as novel antineoplastic agents: A review of traditional use and biomedical investigations. Journal of Ethnopharmacology 2009, 126 (1): 5-17.

7. Tang, Jun; Akao, Teruaki; Nakamura, Norio; Wang, Zheng-Tao; Takagawa, Kiyoshi; Sasahara, Masakiyo; Hattori, Masao*. In vitro metabolism of isoline, a pyrrolizidine alkaloid from Ligularia duciformis, by rodent liver microsomal esterase and enhanced hepatotoxicity by esterase inhibitors. Drug Metabolism and Disposition 2007, 35: 1832-1839.

8. 汤俊*，程敏. 紫草中的吡咯里西啶类成分及其代谢毒性研究进展. 药学学报，2019，54(3): 420-431.

9. 程敏，汤俊*，李姗姗. 紫草萘醌类成分的药理活性及其定量分析方法研究进展. 药学学报，2018，53(12): 2026-2039.

10. 汤俊*，服部征雄. 《中国药典》含吡咯里西啶生物碱的中药品种与用药安全. 药学学报，2011，46(7) : 762-772.