Position: Professor
School/Academic Group: School of Pharmaceutical Sciences
Email: pengfeixu@whu.edu.cn
Education：
2007.09–2012.07 Northwest A&F University, Bachelor
2012.09–2017.07 Beijing Normal University, Ph.D.
Professional Memberships and/or Notable Appointments:
iMeta, Youth Editorial Board
Pharmaceutics, Editorial Board Member
World Journal of Diabetes, Editorial Board Member
International Journal of Molecular Sciences, Editorial Board Member/Guest Editor
Frontiers in Immunology, Guest Editor
Working Experience：
2018.01–2022.01 University of Pittsburgh of Pharmacy, Postdoc
2022/02–2023/02 University of Pittsburgh of Pharmaceutical Sciences, Lecturer
2023/03–Now Wuhan University of Pharmacy, Professor
Research Interests:
Clinical Pharmacology-Basic Research and Medical Translation in Metabolic Diseases
Publications：
1. P. Xu#, Y. Xi#, P. Wang, Z. Luka, M. Xu, H.C. Tung, J. Wang, S. Ren, D. Feng, B.Gao, A. D. Singhi, S. P. Monga, J. D. York, X. Ma, Z. Huang, W. Xie*. Inhibition of p53 sulfoconjugation prevents oxidative hepatotoxicity and acute liver failure. Gastroenterology. 2022 Apr; 162(4): 1226-1241.
2. P. Xu, Y. Xi, J. Zhu, M. Zhang, Z. Luka, D.B. Stolz, X.Cai, Yang Xie, Meishu Xu, Songrong Ren, Zhiying Huang, Da Yang, John D. York, Xiaochao Ma, Wen Xie*. Intestinal Sulfation is Essential to Protect Against Colitis and Colonic Carcinogenesis. Gastroenterology. 2021 Jul; 161(1): 271-286.
3. P. Xu#,*, Y. Xi#, J. Kim , J. Zhu, M. Zhang, M. Xu, S. Ren, D. Yang, X. Ma, W. Xie*.Sulfation of chondroitin and bile acids converges to antagonize Wnt/β-catenin signaling and inhibit APC deficiency-induced gut tumorigenesis. Acta Pharmaceutica Sinica B. 2023 Dec: Doi.org/10.1016/j.apsb.2023.12.006
4. P. Xu, X. Cai, X. Guan, W. Xie*. Sulfoconjugation of protein peptides and glycoproteins in physiology and diseases. Pharmacology & Therapeutics. 2023 Nov: 251: 108540.
5. P. Xu*. Nuclear Receptors in Health and Diseases. International Journal of Molecular Sciences. 2023 May 23; 24(11): 9153.
6. S. Pan, Y. Guo, W. Yu, F. Hong, X. Qiao, J. Zhang, P. Xu*, Y. Zhai*. Environmental chemical TCPOBOP disrupts milk lipid homeostasis during pregnancy and lactation. Ecotoxicology and Environmental Safety. 2023 Jan 1; 114463.
7. J. Li #, *, X. Quan #, Y. Zhang #, T. Yu, S. Lei, Z. Huang, Q. Wang, W. Song, X. Yang, and P. Xu*. PPARγ is Essential in Triclosan Induced Placental Dysfunction. Cells. 2022 Jan; 11(1): 86.
8. P. Ye#, Y. Xi#, Z. Huang, and P. Xu*. Linking Obesity with Colorectal Cancer: Epidemiology and Mechanistic Insights. Cancers. 2020 May 29;12(6):1408.
9. P. Xu, F. Hong, J. Wang, Y. Cong, S. Dai, S. Wang, J. Wang, X. Jin, F. Wang, J. Liu, Y. Zhai*. Microbiome Remodeling via the Montmorillonite Adsorption-Excretion Axis Prevents Obesity-related Metabolic Disorders. eBioMedicine. 2017, Feb; 16: 251-261.
10. P. Xu, J. Wang, F. Hong, S. Wang, X. Jin, T. Xue, L. Jia, Y. Zhai*. Melatonin prevents obesity through modulation of gut microbiota in mice. Journal of Pineal Research. 2017, Mar; 00: e12399.
