Position: Professor

School/Academic Group: School of Pharmaceutical Sciences

Email: dfwu2003@163.com

Education：

1982.09 - 1987.07 Hubei Medical University, School of Clinical Medicine, Bachelor of Medicine

1990.09 - 1993.07 Hubei Medical University, Department of Pharmacology, Master of Medicine

2001.09 - 2005.12 Wuhan University, School of Basic Medical Sciences, Department of Pharmacology, Ph.D.

Professional Memberships and/or Notable Appointments:

Wuhan Pharmacological Society, Council Member

Expert Committee for Health Professional Qualification Examinations (National Health Commission), Member

Chinese Journal of Hospital Pharmacy, Associate Editor-in-Chief

Herald of Medicine, Executive Editorial Board Member

World Clinical Drugs, Editorial Board Member

Working Experience：

1987.07 - 1990.09 Wuhan Metallurgical Medical College, Department of Pharmacology, Lecturer

1993.07 - 2008.02 Renmin Hospital of Wuhan University, Department of Pharmacy

2002.07 - 2002.10 Faculty of Pharmacy, University of Lorraine (Nancy, France), Advanced Training

2003.07 - 2007.10 Department of Cardiovascular Biology, Meharry Medical College (USA)

2008.03 - Present Zhongnan Hospital of Wuhan University, Department of Pharmacy

Current Teaching Interests/Responsibilities:

Clinical Pharmacology

Research Interests:

Molecular Mechanisms of Atherosclerosis and Pharmacological Interventions

Publications：

1.Dongfang Wu, Hong Yang, Yanfeng Zhao, et al. 2-Aminopurine inhibits lipid accumulation induced by apolipoprotein E-deficient lipoprotein in macrophages: potential role eukaryotic initiation factor-2 alpha phosphorylation in foam cell formation. J Pharmacol Exp Ther, 2008; 326(2): 395-405

2.Dongfang Wu, Chakradhari Sharan, Hong Yang, et al. Apolipoprotein E-deficient lipoprotein induce foam cell formation by downregulation of lysosomal hydrolases in macrophages. Journal of Lipid Research, 2007; 48: 2571-2578

3.Dongfang Wu, Hong Yang, Wei Xiang, et al. Heterozygous mutation of ataxia-telangiectasia mutated gene aggravates hypercholesterolemia in apoE-deficient mice. Journal of Lipid Research, 2005; 46(7): 1380-1387

4.Wu Dongfang, Yu Hong and Luo Shunde. Inhibitory effects of sodium ferulate on proliferation of rabbit aortic smooth muscle cells induced by oxidized LDL. Journal of Chinese Pharmaceutical Science, 2001; 10(4): 208-211