Position: Professor
School/Academic Group: School of Pharmaceutical Sciences
Email: Jian.Tian @whu.edu.cn
Education：
1999.09 - 2003.06 College of Chemistry, Nankai University，Bachelor of Science
2004.08 - 2009.12 University of Missouri，Ph.D. in Chemistry
Professional Memberships and/or Notable Appointments:
Chinese Pharmaceutical Association, Member of the Intelligent Pharmaceuticals Professional Committee,
Chinese Chemical Letters, Member of the Youth Editorial Board
Working Experience：
2010.01 - 2013.02 Pacific Northwest National Laboratory，Postdoc
2013.03 – 2015.02 Texas A&M University，Assistant Research Scientist
2015.06 – 2015.12 Department of Chemistry, Rice University，Research Scientist
2015.12 - now Wuhan University, Professor
Current Teaching Interests/Responsibilities:
Pharmaceutics
Research Interests:
Pharmaceutics; Drug delivery materials; Biomaterials
Publications：
1. Jun-Jie Zou, Qing Chen, Phipps Joshua, Yu Zhao, Xudong Qin, Wanyi Tai, Shengqian Ma*, Jian Tian*; Efficient Oral Insulin Delivery with Sustained Release by Folate-Conjugated Metal-Organic Framework Nanoparticles. Matter, 2025, 8: 101948.
2.Haixia Yang, Qing Chen, Huaqiong Qiang*, Bo Wang, Junyang Chen, Yingling Xie, Liyan Peng*, Huanhuan Zhao, Jian Tian*; Corrole-Based Photothermal Nanocomposite Hydrogel with Nitric Oxide Release for Diabetic Wound Healing. Acta Biomaterialia, 2025, 192C, 431-445.
3. Qing Chen, Jin Wang, Xiaoxing Xiong, Junyang Chen, Bo Wang, Haixia Yang, Jianliang Zhou, Hongping Deng*, Lijuan Gu*, Jian Tian*; Blood-Brain Barrier-Penetrating Metal-Organic Framework Antioxidant Nanozymes for Targeted Ischemic Stroke Therapy. Advanced Healthcare Materials, 2024, 202402376.
4. Xin Wang, Xudong Qin, Yi Liu, Yutong Fang, Hao Meng, Meili Shen, Linlin Liu*, Weiwei Huan*, Jian Tian*, Ying-Wei Yang*; Plasmonic Supramolecular Nanozyme-Based Bio-Cockleburs for Synergistic Therapy of Infected Diabetic Wounds. Advanced Materials, 2024, 36, 202411194.
5.Qingjian Lei, Wei Zhou, Shijie Gao, Ningxiang Sun, Bo Wang, Haixia Yang, Jie Wang, Yu Zhao, Qing Chen, Jian Tian*, Lin Cai*, Feifei Yan*; Ultrasound-responsive Metal–Organic Framework-Based Nanosystem for Sonodynamic Therapy/Amplified Ferroptosis/IDO-Blockade Osteosarcoma Immunotherapy. Chemical Engineering Journal, 2024, 490, 151614.
6. Xudong Qin, Rui Tian, Bo Wang, Haixia Yang, Junyang Chen, Xin Wang, Jianliang Zhou*, Qing Chen, Jian Tian*, Ying-Wei Yang*; Multifunctional Metal-Phenolic Nanocapsules with Photothermal Antibacterial and ROS Scavenging Ability for Diabetic Wound Healing. Advanced Healthcare Materials, 2024, 202303604.
7. Yu Zhao, Chen Liang, Zijie Mei, Haixia Yang, Bo Wang, Conghua Xie*, Yu Xu*, Jian Tian*; “Oxygen-Enriched MOF-Hemoglobin X-ray Nanosensitizer for Enhanced Cancer Radio–Radiodynamic Therapy”, ACS Materials Lett. 2023, 5, 3237–3247.
8. Liefeng Hu, Yu Xu, Yu Zhao, Zijie Mei*, Chuxiao Xiong, Jiaying Xiao*, Jiaxi Zhang, Jian Tian*; “Supramolecular nanovesicles with in-situ switchable photothermal/photodynamic effects for precisely controllable cancer phototherapy”, Chemical Engineering Journal, 2023, 476, 146829.
9. Liefeng Hu, Chuxiao Xiong, Jun-Jie Zou, Junrong Chen, Hengyu Lin, Scott J. Dalgarno, Hong-Cai Zhou*, Jian Tian*; “Engineered MOF-Enzyme nanocomposites for tumor microenvironment-activated photodynamic therapy with self-luminescence and oxygen self-supply”, ACS Appl. Mater. Interfaces, 2023, 15, 21, 25369–25381.
10. Yunhao Yu, Rui Tian, Yu Zhao, Xudong Qin, Liefeng Hu, Jun-Jie Zou, Ying-Wei Yang*, Jian Tian*; “Self-Assembled Corrole/Chitosan Photothermal Nanoparticles for Accelerating Infected Diabetic Wound Healing”, Adv. Healthcare Mater., 2023, 2201651.
11. Jun-Jie Zou, Gaohui Wei, Chuxiao Xiong, Yunhao Yu, Sihui Li, Liefeng Hu, Shengqian Ma*, Jian Tian*; “Efficient oral insulin delivery enabled by transferrin-coated acid-resistant metal-organic framework nanoparticles”, Science Advances, 2022, 8(8): eabm4677.
12. Gaohui Wei, Xiang Lian, Xudong Qin, Yu Zhao, Lin Cai*, Qing Chen, Jun-Jie Zou, Jian Tian*; “Core-satellite porphyrinic MOF@CuS nanoconstructs for combined chemodynamic/photodynamic/photothermal therapy”, Materials & Design, 2022, 224: 111302.
13. Liefeng Hu, Chuxiao Xiong, Gaohui Wei, Yunhao Yu, Sihui Li, Xiaoxing Xiong*, Jun-Jie Zou, Jian Tian*; “Stimuli-responsive charge-reversal MOF@polymer hybrid nanocomposites for enhanced codelivery of chemotherapeutics towards combination therapy of multidrug-resistant cancer”, Journal of Colloid and Interface Science, 2022, 608(part 2): 1882-1893.
14. Xin Sun, Guihua He, Chuxiao Xiong, Chenyuan Wang, Xiang Lian, Liefeng Hu, Zhike Li, Scott J. Dalgarno, Ying-Wei Yang*, Jian Tian*; “One-Pot Fabrication of Hollow Porphyrinic MOF Nanoparticles with Ultrahigh Drug Loading toward Controlled Delivery and Synergistic Cancer Therapy”, ACS Appl. Mater. Interfaces, 2021, 13(3): 3679-3693.
15. Zhike Li, Chenyuan Wang, Junrong Chen, Xiang Lian, Chuxiao Xiong, Rui Tian*, Liefeng Hu, Xiaoxing Xiong, Jian Tian*; “uPAR targeted phototheranostic metal-organic framework nanoprobes for MR/NIR-II imaging-guided therapy and surgical resection of glioblastoma”, Materials & Design, 2021, 198: 109386.
