Position: Professor

School/Academic Group: School of Pharmaceutical Sciences

Email: yingfu_lin@whu.edu.cn

Education：

2008.09-2012.06  Tianjin University, Bachelor

2013.09-2017.07  Rutgers University, Ph.D.

2017.08-2018.12  University of Florida, Ph.D

Working Experience：

2019.01-2022.12 University of Michigan–Ann Arbor, Postdoc

2023.01-2023.09 University of Michigan–Ann Arbor, Postdoc

2023.11-now Wuhan University, Professor

Research Interests:

Data Science-Enabled Drug Molecule Design; Innovative Intelligent Synthesis of Bioactive Natural Products and Pharmaceutical Molecules

Publications：

1. “Computer-Aided Key Step Generation in Alkaloid Total Synthesis” Lin, Y.; Zhang, R.; Wang, D.; Cernak, T. Science 2023, 379, 453–457.

2. “Reinforcing the supply chain of umifenovir and other antiviral drugs with retrosynthetic software” Lin, Y.;† Zhang, Z.;† Mahjour, B.; Wang, D.; Zhang, R.; Shim, E.; McGrath, A.; Shen, Y.; Brugger, N.; Turnbull, R.; Trice, S.; Jasty, S.; Cernak, T.* Nat. Commun. 2021, 12, 7327. (†Equal author contributions). Highlighted by the first issue of Nature Synthesis. [It was originally posted on ChemRxiv 2020, Preprint. DOI: 10.26434/chemrxiv.12765410.v1. (†Equal author contributions) Highlighted by C&EN August 17, 2020 Issue and Science News August 7th 2020.]

3. “A Selenourea-Thiourea Brønsted Acid Catalyst Facilitates Asymmetric Conjugate Additions of Amines to α,β-Unsaturated Esters” Lin, Y.; Hirschi, W. J.; Kunadia, A.; Paul, A.; Ghiviriga, I.; Abboud, K. A.; Karugu, R. W.; Vetticatt, M. J.;* Hirschi, J. S.;* Seidel, D.* J. Am. Chem. Soc. 2020, 142, 5627–5635. Highlighted by Synfacts 2020, 16(05), 0579

4. “Catalytic Enantioselective Synthesis of Mariline A and Related Isoindolinones via a Biomimetic Approach.” Min, C.†; Lin, Y.†; Seidel, D.* Angew. Chem. Int. Ed. 2017, 56, 15353–15357 (†Equal author contributions.). Highlighted by Synfacts 2018, 14(01), 0094