Position: Professor
School/Academic Group: School of Pharmaceutical Sciences
Email: yqli@whu.edu.cn
Education：
1997–2002 Wuhan University, Bachelor
2002–2005 Wuhan University/Beijing 301 Hospital/Second Artillery General Hospital, Master
2005–2008 Peking University, Ph.D.
Professional Memberships and/or Notable Appointments:
Hubei Medical Association – Council Member
Drug Epidemiology and Drug Evaluation Specialty Committee, Hubei Pharmaceutical Association – Committee Member
Hubei Pharmacological Society – Council Member
Wuhan Pharmacological Society – Council Member
Popular Science Branch, China Ethnic Medicine Association – Council Member
Drug Dependence Specialty Committee, Chinese Society of Toxicology – Committee Member
National Natural Science Foundation of China, Key R&D Programs of the Ministry of Science and Technology, WHO International Projects under the Ministry of Science and Technology, etc. – Review Expert
Working Experience：
2008–2010 University of Pittsburgh Medical Center in Pharmacology, Postdoc
2011–Present Wuhan University, School of Pharmaceutical Sciences, Associate Professor, Professor
Current Teaching Interests/Responsibilities:
Pharmacology, Pathophysiology
Research Interests:
Mechanism Research and Target Validation for Neuropsychiatric Diseases;Targeted Drug Development for Avoiding Addiction to Narcotic and Psychotropic Drugs; Precision Diagnosis and Monitoring Technology and Product Development; Preclinical Evaluation, Translation, and Clinical Research of New Drugs
Publications：
1.Zhu S, Chen P, Chen M, Ruan J, Ren W, Zhang X, Gao Y and Li Y *.(2020/01).Alcohol inhibits morphine/ cocaine reward memory acquisition and reconsolidation in rats.Psychopharmacology (Berl).2020 Apr;237(4):1043-1053.
2．Gao Y, Peng S, Wen Q, Zheng C, Lin J, Tan Y, Ma Y, Luo Y, Xue Y, Wu P, Ding Z, Lu L and Li Y * The mammalian target of rapamycin pathway in basolateral amygdala is critical for nicotine-induced behavioral sensitization. Int J Neuropsychopharmacol. 2014.
3. Lin J, Liu L, Wen Q, Zheng C, Gao Y, Peng S , Tan Y and Li, Y *. Rapamycin prevents drug seeking via disrupting reconsolidation of reward memory in rats. Int J Neuropsychopharma -col. 2014 Jan;17(1):127-36.Epub 2013 Oct 8.
4. Li YQ, Xue YX, He YY, Li FQ, Xue LF, Xu CM, Sacktor TC, Shaham Y, Lu L. Inhibition of PKMzeta in nucleus accumbens core abolishes long-term drug reward memory. J Neurosci. 2011 Apr 6;31(14):5436-46.
5. Li YQ, Li FQ, Wang XY, Wu P, Zhao M, Xu CM, Shaham Y, Lu L. Central amygdala ERK signaling pathway is critical to incubation of opiate craving. J Neurosci. 2008 Dec 3;28(49):13248-57.
6. Li YQ, Wang XY, Zhai HF, Zheng YQ, Zhang XY, Kosten T, Lu L.. Effects of early postnatal sibling deprivation on anxiety and vulnerability to cocaine in offspring rats. Psychopharmacology (Berl). 2008 Aug;199(2):245-53.
7. Li YQ, Wang XY, Zhai HF, Zhang XY, Kosten T, Lu L. Sex- and age-dependent effects of early postnatal sibling deprivation on spatial learning and memory in adult rats. Behav Brain Res. 2008 Jan 10;186(1):138-42.
8. Zhai H, Li YQ (co-first author), Wang X, Lu L.. Drug-induced alterations in extracellular signal-regulated kinase (ERK) signalling pathway: implications for reinforcement and reinstatement (review). Cell Mol Neurobiol. 2008 Feb;28(2):157-72.
9. Fang Q, Li FQ, Li YQ, Xue YX, He YY, Liu JF, Lu L, Wang JS. Cannabinoid CB(1) receptor antagonist rimonabant disrupts nicotine reward-associated memory in rats. Pharmacol Biochem Behav. 2011 Oct; 99(4):738-42.
10. Li FQ, Xue YX, Wang JS, Fang Q, Li YQ, Zhu WL, He YY, Liu JF, Xue LF, Shaham Y, Lu L. Basolateral amygdala Cdk5/p35 activity mediates cocaine rewarding memory. J Neurosci, 2010 Aug 4;30(31):10351-9.
11. Yu LL, Wang XY, Zhao M, Liu Y, Li YQ, Li FQ, Wang X, Xue YX, Lu L. Effects of cannabinoid CB1 receptor antagonist rimonabant in consolidation and reconsolidation of methamphetamine reward memory in mice. Psychopharmacology (Berl). 2009 Jun;204(2):203-11.
12. Wang XY, Zhao M, Ghitza UE, Li YQ, Lu L. Stress impairs reconsolidation of drug memory via glucocorticoid receptors in the basolateral amygdale. J Neurosci. 2008 May 21;28(21):5602-10. 13. Liu J, Li YQ , Ouyang JP et al. Protective effects of NADH on cardiac fibroblasts apoptosis induced by hydrazine. Med J Chin PLA. 2008. 33: 305-307.
14. Li YQ , Liu J, Ouyang JP , et al. The mechanism of the apoptosis of cardiac fibroblast induced by hydrazine. Chin J Aerospace Med, 2006.17: 176-179.
15. Li YQ , Liu J, Ouyang JP , et al. Effect of hydrazine on Proliferation and apoptosis of cardiac fibroblast. Medical Journal of Wuhan University. 2005. 26: 326-328.
