Position: Professor
School/Academic Group: School of Pharmaceutical Sciences
Email: weili.mn@whu.edu.cn
Education：
2005.09 - 2009.06 Huazhong University of Science and Technology，Bachelor
2009.09 - 2012.03 Huazhong University of Science and Technology，Master
2012.09 - 2015.10 City University of Hong Kong，Ph.D.
Professional Memberships and/or Notable Appointments:
Chinese Journal of Pharmaceuticals, Member of the Editorial Board
Chinese Chemical Letters, Member of the Youth Editorial Board
Acta Medica Materia, Member of the Youth Editorial Board
Pharmaceutical Fronts, Member of the Youth Editorial Board
BMEMat, Member of the Youth Editorial Board
Frontiers in Microbiology, Guest Editor
Working Experience：
2016.02-2020.09 Georgia Institute of Technology，Postdoc
2020.10-now Wuhan University, Professor
Current Teaching Interests/Responsibilities:
Pharmaceutics
Research Interests:
Microneedles; Drug delivery; Transdermal drug delivery; Sustained release
Publications：
1. W. Li, Jie Tang, Dennis Lee, Thomas Tice, Steven Schwendeman, and Mark Prausnitz*, “Clinical Translation of Long-acting Drug Delivery Formulations” Nature Reviews Materials，7，406-420（2022）
2. W. Li, R. Terry, J. Tang, M. Feng, S. Schwendeman, M. Prausnitz*, “Rapidly Separable Microneedle Patch for the Sustained Release of a Contraceptive” Nature Biomedical Engineering, 3: 220-29 (2019) (Highlighted by Nature Biomedical Engineering, Nature Reviews Materials, Science Daily and homepage of Georgia Institute of Technology)
3. W. Li, J. Tang, R. Terry, S. Li, A. Brunie, R. Callahan, R. Noel, C. Rodriguez, S. Schwendeman, M. Prausnitz*, “Long-acting Reversible Contraception by Effervescent Microneedle Patch”, Science Advances, 5 (11), eaaw8145 (2019)
4. C. Wang, G. He, H. Zhao, Y. Lu, P. Jiang*, W. Li*, Enhancing Deep-Seated Melanoma Therapy through Wearable Self-Powered Microneedle Patch, Advanced Materials, 2311246 (2024).
5. X. Jiang, Y. Jin, Y. Zeng, P. Shi, W. Li*, Self-Implantable Core-Shell Microneedle Patch for Long-Acting Treatment of Keratitis via Programmed Drug Release, Small, e2310461 (2024)
6. Y. Zeng, C. Wang, J. Lei, X. Jiang, K. Lei, Y. Jin, T. Hao, W. Zhang, J. Huang *, W. Li*, “Spatiotemporally responsive cascade bilayer microneedles integrating local glucose depletion and sustained nitric oxide release for accelerated diabetic wound healing”, Acta Pharmaceutica Sinica B, (2024)
7. Y. Jin, Y. Lu, X. Jiang, M. Wang, Y. Yuan, Y. Zeng, L. Guo*, W. Li*, “Accelerated infected wound healing by probiotic-based living microneedles with long-acting antibacterial effect”, Bioactive Materials, 38, 292-304 (2024)
8. C. Wang#, Y. Zeng#, K. Chen, J. Lin, Q. Yuan, X. Jiang, G. Wu, F. Wang*, Y. Jia*, W. Li*, “A self-monitoring microneedle patch for light-controlled synergistic treatment of melanoma”, Bioactive Materials, 27,58-71 (2023).
9. H. Yang, X. Jiang, Y. Zeng, W. Zhang, Q. Yuan, M. Yin, G. Wu, W. Li*,“A swellable bilateral microneedle patch with core-shell structure for rapid lactate analysis and early melanoma diagnosis”，Chemical Engineering Journal, 455,140730 (2023).
10. A. Zhang, Y. Zeng, B. Xiong, X. Jiang, Y. Jin, S. Wang, Y. Yuan, W. Li,* and M. Peng*, “A pH-Responsive Core-Shell Microneedle Patch with Self-Monitoring Capability for Local Long-Lasting Analgesia”, Advanced Functional Materials, 2314048 (2023).
11. Y. Zeng#, C. Wang#, K. Lei, C. Xiao, X. Jiang, W. Zhang, L. Wu, J. Huang*, W. Li*,“Multifunctional MOF-based Microneedle Patch with Synergistic Chemo-photodynamic Antibacterial Effect and Sustained Release of Growth Factor for Chronic Wound Healing”，Advanced Healthcare Materials, 2300250 (2023).
12. M. Yin#, Y. Zeng#, H. Liu#, W. Zhang, C. Wang, C. Chen*, W. Li*,“Dissolving Microneedle Patch Integrated with Microspheres for Long-Acting Hair Regrowth Therapy”, ACS Applied Materials and Interfaces, 15, 17532-17542 (2023).
13. W. Li*, J. Chen, R. Terry, J. Tang, A. Romanyuk, S. Schwendeman, M. Prausnitz*,“Core-shell microneedle patch for six-month controlled-release contraceptive delivery”, Journal of Controlled Release，347，489-499 (2022).
14. W. Li#*, S Li#, X Fan, MR Prausnitz*, “Microneedle patch designs to increase dose administered to human subjects”, Journal of Controlled Release，339，350-360 (2021)
15. X. Jiang, H. Zhao, W. Li*, “Microneedle-mediated Transdermal Delivery of Drug-carrying Nanoparticles”, Frontiers in Bioengineering and Biotechnology, 10, 840395 (2022)
16. C. Wang, X. Jiang, Y. Zeng, R. Terry, W. Li*, “Rapidly separable microneedle patches for controlled release of therapeutics for long-acting therapies”, Medicine in Drug Discovery, 13, 100118 (2022)
17. M. Prausnitz*, Y. Gomaa, W. Li, “Microneedle Patch Drug Delivery in The Gut”, Nature Medicine, 25, 1471--1472 (2019)
18. Y. Lee, W. Li, J. Tang, S. Schwendeman, M. Prausnitz “Immediate detachment of microneedles by interfacial fracture for sustained delivery of a contraceptive hormone in the skin”, Journal of Controlled Release, 337:676-685 (2021)
