田间（Jian Tian）
职务/职称：三级教授、博士生导师
通讯地址：湖北省武汉市武昌区东湖路185号太阳集团tyc234cc
课题组地址：太阳成集团tyc234cc医学部一号楼四楼431-433室
学习与工作简历：
1999年9月至2003年6月 南开大学化学学院获理学学士学位
2004年8月至2009年12月 美国密苏里大学哥伦比亚分校获化学博士学位
2010年1月至2013年2月 美国西北太平洋国家实验室博士后研究人员
2013年3月至2015年2月 美国德克萨斯农工大学研究助理科学家
2015年6月至2015年12月 美国莱斯大学化学系项目研究科学家
2015年12月至今 太阳集团tyc234cc，教授，博士生导师
研究方向：
药剂学、药物材料、生物材料
1. 基于金属有机骨架载体的生物大分子药物递送系统
2. 多模态分子影像纳米载体的设计、构筑和诊疗一体化应用
3. 放射治疗增敏联合免疫治疗抗肿瘤研究
业绩概要：
长期从事基于金属有机骨架的新型药用功能材料与药物递送系统的研究，以第一或(共同)通讯作者在Sci Adv、Matter、J. Am. Chem. Soc.、Angew. Chem., Int. Ed.、Adv Mater等高水平SCI期刊上发表论文20余篇。总计发表SCI论文50余篇，他引7000余次, H指数为33。相关研究成果被著名媒体C&EN作为 “News of the Week” 专题报道两次，有关口服胰岛素递送的研究成果被科技部网站和《湖北日报》专题推荐。受邀担任中国药学会智能药物专业委员会委员，《Chinese Chemical Letters》青年编委，Nat. Comm.、J. Am. Chem. Soc.、Adv Mater、Adv Sci等十余种SCI期刊审稿人。
在研项目：
国际自然科学基金项目、湖北省科技厅重大专项、太阳成集团tyc234cc自主科研项目等。
招生招聘
1. 诚挚欢迎坚韧、勤奋、有理想的硕士博士研究生（具有药学、化学、生物或材料专业背景皆可）一起共同探索药剂学方向的交叉学科研究。欢迎有志于进入本课题组读研的本科生加入业余科研或定向培养。
2. 诚聘药剂学研究方向博士后1名，为博士后提供25-30万元年薪。
3. 诚聘药学、生物、医学专业背景科研助理一名。
代表性论文（任现职以来）：
(1) Jun-Jie Zou, Qing Chen, Phipps Joshua, Yu Zhao, Xudong Qin, Wanyi Tai, Shengqian Ma*, Jian Tian*; Efficient Oral Insulin Delivery with Sustained Release by Folate-Conjugated Metal-Organic Framework Nanoparticles. Matter, 2025, 8: 101948.
(2) Haixia Yang, Qing Chen, Huaqiong Qiang*, Bo Wang, Junyang Chen, Yingling Xie, Liyan Peng*, Huanhuan Zhao, Jian Tian*; Corrole-Based Photothermal Nanocomposite Hydrogel with Nitric Oxide Release for Diabetic Wound Healing. Acta Biomaterialia, 2025, 192C, 431-445.
(3) Qing Chen, Jin Wang, Xiaoxing Xiong, Junyang Chen, Bo Wang, Haixia Yang, Jianliang Zhou, Hongping Deng*, Lijuan Gu*, Jian Tian*; Blood-Brain Barrier-Penetrating Metal-Organic Framework Antioxidant Nanozymes for Targeted Ischemic Stroke Therapy. Advanced Healthcare Materials, 2024, 202402376.
(4) Xin Wang, Xudong Qin, Yi Liu, Yutong Fang, Hao Meng, Meili Shen, Linlin Liu*, Weiwei Huan*, Jian Tian*, Ying-Wei Yang*; Plasmonic Supramolecular Nanozyme-Based Bio-Cockleburs for Synergistic Therapy of Infected Diabetic Wounds. Advanced Materials, 2024, 36, 202411194.
(5) Qingjian Lei, Wei Zhou, Shijie Gao, Ningxiang Sun, Bo Wang, Haixia Yang, Jie Wang, Yu
Zhao, Qing Chen, Jian Tian*, Lin Cai*, Feifei Yan*; Ultrasound-responsive Metal–Organic Framework-Based Nanosystem for Sonodynamic Therapy/Amplified Ferroptosis/IDO-Blockade Osteosarcoma Immunotherapy. Chemical Engineering Journal, 2024, 490, 151614.
(6) Xudong Qin, Rui Tian, Bo Wang, Haixia Yang, Junyang Chen, Xin Wang, Jianliang Zhou*, Qing Chen, Jian Tian*, Ying-Wei Yang*; Multifunctional Metal-Phenolic Nanocapsules with Photothermal Antibacterial and ROS Scavenging Ability for Diabetic Wound Healing. Advanced Healthcare Materials, 2024, 202303604.
(7) Yu Zhao, Chen Liang, Zijie Mei, Haixia Yang, Bo Wang, Conghua Xie*, Yu Xu*, Jian Tian*; “Oxygen-Enriched MOF-Hemoglobin X-ray Nanosensitizer for Enhanced Cancer Radio–Radiodynamic Therapy”, ACS Materials Lett. 2023, 5, 3237–3247.
(8) Liefeng Hu, Yu Xu, Yu Zhao, Zijie Mei*, Chuxiao Xiong, Jiaying Xiao*, Jiaxi Zhang, Jian Tian*; “Supramolecular nanovesicles with in-situ switchable photothermal/photodynamic effects for precisely controllable cancer phototherapy”, Chemical Engineering Journal, 2023, 476, 146829.
(9) Liefeng Hu, Chuxiao Xiong, Jun-Jie Zou, Junrong Chen, Hengyu Lin, Scott J. Dalgarno, Hong-Cai Zhou*, Jian Tian*; “Engineered MOF-Enzyme nanocomposites for tumor microenvironment-activated photodynamic therapy with self-luminescence and oxygen self-supply”, ACS Appl. Mater. Interfaces, 2023, 15, 21, 25369–25381.
(10) Yunhao Yu, Rui Tian, Yu Zhao, Xudong Qin, Liefeng Hu, Jun-Jie Zou, Ying-Wei Yang*, Jian Tian*; “Self-Assembled Corrole/Chitosan Photothermal Nanoparticles for Accelerating Infected Diabetic Wound Healing”, Adv. Healthcare Mater., 2023, 2201651.
(11) Jun-Jie Zou, Gaohui Wei, Chuxiao Xiong, Yunhao Yu, Sihui Li, Liefeng Hu, Shengqian Ma*, Jian Tian*; “Efficient oral insulin delivery enabled by transferrin-coated acid-resistant metal-organic framework nanoparticles”, Science Advances, 2022, 8(8): eabm4677.
(12) Gaohui Wei, Xiang Lian, Xudong Qin, Yu Zhao, Lin Cai*, Qing Chen, Jun-Jie Zou, Jian Tian*; “Core-satellite porphyrinic MOF@CuS nanoconstructs for combined chemodynamic/photodynamic/photothermal therapy”, Materials & Design, 2022, 224: 111302.
(13) Liefeng Hu, Chuxiao Xiong, Gaohui Wei, Yunhao Yu, Sihui Li, Xiaoxing Xiong*, Jun-Jie Zou, Jian Tian*; “Stimuli-responsive charge-reversal MOF@polymer hybrid nanocomposites for enhanced codelivery of chemotherapeutics towards combination therapy of multidrug-resistant cancer”, Journal of Colloid and Interface Science, 2022, 608(part 2): 1882-1893.
(14) Xin Sun, Guihua He, Chuxiao Xiong, Chenyuan Wang, Xiang Lian, Liefeng Hu, Zhike Li, Scott J. Dalgarno, Ying-Wei Yang*, Jian Tian*; “One-Pot Fabrication of Hollow Porphyrinic MOF Nanoparticles with Ultrahigh Drug Loading toward Controlled Delivery and Synergistic Cancer Therapy”, ACS Appl. Mater. Interfaces, 2021, 13(3): 3679-3693.
(15) Zhike Li, Chenyuan Wang, Junrong Chen, Xiang Lian, Chuxiao Xiong, Rui Tian*, Liefeng Hu, Xiaoxing Xiong, Jian Tian*; “uPAR targeted phototheranostic metal-organic framework nanoprobes for MR/NIR-II imaging-guided therapy and surgical resection of glioblastoma”, Materials & Design, 2021, 198: 109386.
